{"id":296,"date":"2019-07-24T10:28:15","date_gmt":"2019-07-24T02:28:15","guid":{"rendered":"\/\/www.5080666.com\/product\/aureobasidin-a-%ef%bc%88aba%ef%bc%89%e9%87%91%e6%8b%85%e5%ad%90%e7%b4%a0a%ef%bc%881-mg-ml%ef%bc%89\/"},"modified":"2021-11-25T10:41:24","modified_gmt":"2021-11-25T02:41:24","slug":"aureobasidin-a-%ef%bc%88aba%ef%bc%89%e9%87%91%e6%8b%85%e5%ad%90%e7%b4%a0a%ef%bc%881-mg-ml%ef%bc%89","status":"publish","type":"product","link":"\/\/www.5080666.com\/product\/aureobasidin-a-%ef%bc%88aba%ef%bc%89%e9%87%91%e6%8b%85%e5%ad%90%e7%b4%a0a%ef%bc%881-mg-ml%ef%bc%89\/","title":{"rendered":"Aureobasidin A \uff08AbA\uff09\u91d1\u62c5\u5b50\u7d20A\uff081 mg\/ml\uff09"},"content":{"rendered":"

Aureobasidin A\uff08AbA\uff09\u91d1\u62c5\u5b50\u7d20A<\/strong><\/span><\/p>\n

\u4ea7\u54c1\u6807\u7b7e<\/strong><\/span><\/p>\n

\u9009\u62e9\u6027\u6297\u751f\u7d20\uff1b\u9175\u6bcd\u83cc\u8f6c\u5316\u7cfb\u7edf\u3010\u917f\u9152\u9175\u6bcd\u3001\u7c9f\u9152\u88c2\u6b96\u9175\u6bcd\u3001\u5ff5\u73e0\u83cc\u3011\uff1b\u771f\u83cc\u8f6c\u5316\u7cfb\u7edf\u3010\u6784\u5de2\u66f2\u9709\u3001\u9ed1\u66f2\u9709\u3011\uff1b\u9175\u6bcd\u5355\u6742\u4ea4\/\u53cc\u6742\u4ea4\uff1bAUR1\u57fa\u56e0\uff1bAURA\u57fa\u56e0\uff1bIPAC\u5408\u6210\u9176\uff1bAUR1-C\u7a81\u53d8\u57fa\u56e0\uff1b<\/span><\/p>\n

\u4ea7\u54c1\u4fe1\u606f<\/strong><\/span><\/p>\n\n\n\n\n\n\n
\n

\u4ea7\u54c1\u540d\u79f0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n<\/td>\n

\u4ea7\u54c1\u7f16\u53f7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/td>\n\u89c4\u683c\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/td>\n\u4ef7\u683c\uff08\u5143\uff09\u00a0\u00a0<\/span><\/td>\n<\/tr>\n
\n

Aureobasidin A\uff08AbA\uff09\u91d1\u62c5\u5b50\u7d20A\uff081 mg\/ml\uff09<\/span><\/p>\n<\/td>\n

MS0002-1ML<\/span><\/td>\n1ml<\/span><\/td>\n1200<\/span><\/td>\n<\/tr>\n
Aureobasidin A\uff08AbA\uff09\u91d1\u62c5\u5b50\u7d20A\uff081 mg\/ml\uff09<\/span><\/td>\nMS0002-5ML<\/span><\/td>\n5\u00d71ml<\/span><\/td>\n\n

5400<\/span><\/p>\n<\/td>\n<\/tr>\n

Aureobasidin A\uff08AbA\uff09\u91d1\u62c5\u5b50\u7d20A\uff08\u51bb\u5e72\u7c89\uff09<\/span><\/td>\nMS0002-10MG<\/span><\/td>\n10mg<\/span><\/td>\n\n

8800<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u3010\u6e29\u99a8\u63d0\u793a\u3011\uff1a<\/strong>\u89c1\u6211\u53f8\u6574\u7406\u7684\u9175\u6bcd\u53cc\u6742\u4ea4\u68c0\u6d4b\uff08Yeast two-hybrid assay\uff09\u4ea7\u54c1\u4e13\u9898<\/a><\/strong><\/u>\u3002<\/span><\/p>\n

\u4ea7\u54c1\u63cf\u8ff0<\/strong><\/span><\/p>\n

\u91d1\u62c5\u5b50\u7d20A\uff08Aureobasidin A\uff0cAbA\uff09\uff0c\u4e5f\u79f0\u4e3a\u77ed\u6897\u9709\u7d20A\uff0c\u4e00\u79cd\u6765\u6e90\u4e8e\u4e1d\u72b6\u771f\u83ccAureobasidium pullulansNo. R106\u7684\u73af\u916f\u80bd\u7c7b\u6297\u771f\u83cc\u6297\u751f\u7d20\uff0c\u5728\u8f83\u4f4e\u6d53\u5ea6\uff080.1-0.5\u03bcg\/ml\uff09\u4e0b\u5373\u53ef\u5bf9\u9175\u6bcd\u83cc\u4ea7\u751f\u6bd2\u6027\uff0c\u5bf9\u8be5\u6297\u751f\u7d20\u654f\u611f\u7684\u771f\u83cc\u5305\u62ec\uff1a\u917f\u9152\u9175\u6bcd\uff08Saccharomyces cerevisiae\uff09\uff0c\u7c9f\u9152\u88c2\u6b96\u9175\u6bcd\uff08Schizosaccharomyces pombe\uff09\u3001\u5149\u6ed1\u5ff5\u73e0\u83cc\uff08Candida glabrata\uff09\u3001\u6784\u5de2\u66f2\u9709\uff08Aspergillus nidulans\uff09\u548c\u9ed1\u66f2\u9709\uff08Aspergillusniger.\uff09\u3002\u91d1\u62c5\u5b50\u7d20AbA\u901a\u8fc7\u6291\u5236\u771f\u83cc\u751f\u957f\u6240\u4f9d\u8d56\u7684\u808c\u9187\u78f7\u8102\u9170\u795e\u7ecf\u9170\u80fa\u5408\u6210\u9176\uff08Inositol phosphorylceramide (IPC) synthase\uff09\u6d3b\u6027\uff0c\u963b\u788d\u795e\u7ecf\u9170\u80fa\u5230\u808c\u9187\u78f7\u8102\u9170\u795e\u7ecf\u9170\u80fa\u7684\u5408\u6210\uff0c\u5bfc\u81f4\u9798\u8102\u7c7b\u7269\u8d28\u7684\u5408\u6210\u91cf\u4e0d\u8db3\uff0c\u7ec6\u80de\u819c\u7834\u88c2\uff0c\u8fdb\u800c\u6740\u6b7b\u83cc\u682a\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u6765\u81ea\u917f\u9152\u9175\u6bcd\u83cc\u7684AUR1\u548c\u6784\u5de2\u66f2\u9709\u7684AURA\u57fa\u56e0\uff0c\u4e24\u8005\u5177\u6709\u540c\u6e90\u6027\uff0c\u90fd\u80fd\u591f\u7f16\u7801IPC\u5408\u6210\u9176\uff0c\u5bf9\u8fd9\u4e24\u79cd\u57fa\u56e0\u7684\u70b9\u7a81\u53d8\uff0c\u4e5f\u90fd\u8d4b\u4e88\u83cc\u682a\u5bf9AbA\u4ea7\u751f\u5f88\u5f3a\u7684\u6297\u6027\uff0c\u6bd4\u5982\uff1a\u7a81\u53d8\u57fa\u56e0AUR1-C\u3002<\/span><\/p>\n

\u9175\u6bcd\u8f6c\u5316\u7814\u7a76\u4e2d\uff0c\u91d1\u62c5\u5b50\u7d20A\uff08AbA\uff09\u662f\u4e00\u79cd\u975e\u5e38\u6709\u6548\u7684\u9009\u62e9\u6027\u6807\u5fd7\uff0c\u4f7f\u7528\u4e0a\u57fa\u672c\u4e0d\u9700\u4f18\u5316\u6761\u4ef6\uff0c\u4e14\u521b\u9020\u6781\u4f4e\u80cc\u666f\u3002AbA\u6297\u6027\u662f\u9175\u6bcd\u53cc\u6742\u4ea4\u7814\u7a76\u4e2d\u7406\u60f3\u7684\u62a5\u544a\u5b50\uff0c\u517c\u5bb9\u4e8e\u643a\u5e26\u76f8\u5e94\u6297\u6027\u7684\u9175\u6bcd\u5355\u6742\u4ea4\/\u53cc\u6742\u4ea4\u7cfb\u7edf\uff0c\u5e76\u63d0\u4f9b\u826f\u597d\u7684\u7b5b\u9009\u7ed3\u679c\u3002<\/span><\/p>\n

\u6211\u53f8\u63d0\u4f9b\u4e24\u79cd\u5f62\u5f0f\u7684\u672c\u54c1\uff0c\u4e00\u79cd\u4ee5\u6eb6\u4e8e\u7532\u9187\u7684\u50a8\u5b58\u6db2\u5f62\u5f0f\u63d0\u4f9b\uff0c\u6d53\u5ea61mg\/ml\uff0c\u4e14\u89c4\u683c\u5c0f\uff0c\u9002\u5408\u9700\u91cf\u8f83\u5c11\u7528\u6237\uff0c\u7ecf\u6d4e\u5b9e\u60e0\uff1b\u4e00\u79cd\u4ee5\u51bb\u5e72\u7c89\u5f62\u5f0f\u63d0\u4f9b\uff0c\u8fd0\u8f93\u65b9\u4fbf\u4e14\u7a33\u5b9a\u6027\u76f8\u5bf9\u8f83\u9ad8\uff0c\u9002\u5408\u9700\u91cf\u591a\u7684\u7528\u6237\u3002AbA\u5e38\u7528\u7b5b\u9009\u6d53\u5ea6\u4e3a100-200ng\/ml\uff0c\u5177\u4f53\u7684\u7b5b\u9009\u6d53\u5ea6\u53d6\u51b3\u4e8e\u5bbf\u4e3b\u7ec6\u80de\u7684\u654f\u611f\u5ea6\u3010\u89c1\u9644\u88681\u3011\u3002<\/span><\/p>\n

\u4ea7\u54c1\u7279\u6027<\/strong><\/span><\/p>\n

1\uff09\u540c\u4e49\u540d\uff1a\u77ed\u6897\u9709\u7d20A<\/span><\/p>\n

2\uff09\u5206\u5b50\u5f0f\uff1aC60H92N8O11<\/span><\/p>\n

3\uff09\u5206\u5b50\u91cf\uff1a1100Da<\/span><\/p>\n

4\uff09\u7eaf\u5ea6\uff1a\u226595%<\/span><\/p>\n

5\uff09\u7194\u70b9\uff1a155-157\u2103<\/span><\/p>\n

6\uff09\u6eb6\u89e3\u6027\uff1a\u7c89\u672b\u4e0d\u6eb6\u4e8e\u6c34\uff0c\u6613\u6eb6\u4e8e\u7532\u9187\u3001\u4e59\u9187\uff080.5-5mg\/ml\uff09<\/span><\/p>\n

7\uff09\u5316\u5b66\u7ed3\u6784\u5f0f\uff1a \"\"<\/span><\/p>\n

\u4fdd\u5b58\u4e0e\u8fd0\u8f93\u65b9\u6cd5<\/strong><\/span><\/p>\n

\u4fdd\u5b58\uff1a\u51bb\u5e72\u7c89\u5ba4\u6e29\u4fdd\u5b58\uff0c\u81f3\u5c111\u5e74\u6709\u6548\uff1b\u50a8\u5b58\u6db2\uff081mg\/ml\uff09\u7f6e\u4e8e2-8\u2103\u4fdd\u5b58\uff0c\u81f3\u5c116\u4e2a\u6708\u6709\u6548\u3002<\/span><\/p>\n

\u8fd0\u8f93\uff1a\u51bb\u5e72\u7c89\u5ba4\u6e29\u8fd0\u8f93\uff0c\u50a8\u5b58\u6db2\uff081mg\/ml\uff09\u51b0\u888b\u8fd0\u8f93\u3002<\/span><\/p>\n

\u4f7f\u7528\u65b9\u6cd5<\/strong><\/span><\/p>\n

1\uff09\u5bf9\u4e8e\u91d1\u62c5\u5b50\u7d20A\uff081 mg\/ml\uff09\u50a8\u5b58\u6db2\uff08\u8d27\u53f7\uff1aMS0002-1ML\uff0cMS0002-5ML\uff09\uff1a\u76f4\u63a5\u7528\u9175\u6bcd\u57f9\u517b\u57fa\u7a00\u91ca\u5230\u6240\u9700\u7684\u7b5b\u9009\u6d53\u5ea6\uff0c\u5e38\u7528\u7684\u7b5b\u9009\u6d53\u5ea6\u4e3a100-200ng\/ml\uff0c\u5177\u4f53\u7684\u7b5b\u9009\u6d53\u5ea6\u53d7\u5bbf\u4e3b\u7ec6\u80de\u7684\u654f\u611f\u5ea6\u5f71\u54cd\u3002<\/span><\/p>\n

2\uff09\u5bf9\u4e8e\u91d1\u62c5\u5b50\u7d20A\u7c89\u672b\uff08\u8d27\u53f7\uff1aMS0002-10MG\uff09\uff1a\u7528\u65e0\u6c34\u4e59\u9187\u6216\u7532\u9187\u5c06\u7c89\u672b\u4f1a\u4ece\u5206\u6eb6\u89e3\u914d\u5236\u62100.5-5mg\/ml\u50a8\u5b58\u6db2\uff0c2-8\u2103\u4fdd\u5b58\u3002\u5b9e\u9a8c\u524d\uff0c\u7528\u9175\u6bcd\u57f9\u517b\u57fa\u7a00\u91ca\u5230\u6240\u9700\u7b5b\u9009\u6d53\u5ea6\u5373\u53ef\u3002<\/span><\/p>\n

\u5e94\u7528\u793a\u4f8b\uff08\u6765\u81ea\u6587\u732e\u8d44\u6e90\uff09<\/strong><\/span><\/p>\n

A.\u9175\u6bcd\u5355\u6742\u7cfb\u7edfY1Hgold\uff1a<\/span><\/p>\n

\u6587\u732e\u2460:The screening and functional study of proteins binding with the BmNPV polyhedrin promoter.PMID: 22559085<\/span><\/p>\n

\u7528\u91cf\uff1a\u7528\u6765\u6291\u5236Y1HGold (p53-AbAi)\u9175\u6bcd\u83cc\u682a\u57fa\u7840\u8868\u8fbe\u7684AbA\u6700\u4f4e\u6d53\u5ea6\u4e3a200ng\/ml\uff1b\u7528\u6765\u6291\u5236Y1HGold (p3rep-AbAi)\u548cY1HGold (p3mut-AbAi])\u9175\u6bcd\u83cc\u682a\u57fa\u7840\u8868\u8fbe\u7684AbA\u6700\u4f4e\u6d53\u5ea6\u4e3a300ng\/ml\u3002<\/span><\/p>\n

\u6587\u732e\u2461:BjMYB1, a transcription factor implicated in plant defence through activating BjCHI1 chitinase expression by binding to a W-box-like element. PMID: 27353280<\/span><\/p>\n

\u7528\u91cf\uff1a\u4e3a\u4e86\u5f00\u5c55Y1H\u7b5b\u9009\uff0c\u7528\u6765\u6291\u5236Y1Hgold [pBait-AbAi]\u548cY1Hgold [pBait-m-AbAi]\u9175\u6bcd\u83cc\u751f\u957f\u7684AbA\u6700\u4f4e\u6291\u5236\u6d53\u5ea6\u5728SD\/\u2212Ura\/+AbA\u57f9\u517b\u57fa\u4e0a\u9996\u5148\u786e\u8ba4\u540e\u4e3a550ng\/ml\u3002<\/span><\/p>\n

\u6587\u732e\u2462\uff1aTwo Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.PMID: 28710291<\/span><\/p>\n

\u7528\u91cf\uff1a\u7b2c\u4e00\u6b21\u7b5b\u9009\uff0ccDNA\u548c\u7ebf\u6027pGADT7\u8f7d\u4f53\u5171\u8f6c\u5316\u8fdb\u5165Y1HGold [Hx-pAbAi]\uff0c\u8f6c\u5316\u5b50\u6d82\u5e03\u5728\u542b200ng\/ml AbA\u7684SD-Leu\u57f9\u517b\u57fa\u3002<\/span><\/p>\n

B.\u9175\u6bcd\u53cc\u6742\u7cfb\u7edfY2Hgold\uff1a<\/span><\/p>\n

\u6587\u732e\u2460:PbTTG1 forms a ribonucleoprotein complex with polypyrimidine tract-binding protein PbPTB3 to facilitate the long-distance trafficking of PbWoxT1 mRNA. PMID: 30824022<\/span><\/p>\n

\u7528\u91cf\uff1a\u7b80\u8a00\u4e4b\uff0c\u8f6c\u5316\u8fdbpGBKT7-PbPTB3\u7684Y2HGold\u7528\u4f5c\u8bf1\u9975\u6765\u7b5b\u9009\u542bpGADT7\u8f7d\u4f53\u7684Y187\uff08\u542bcDNA\u6587\u5e93\uff09\u8f6c\u5316\u5b50\u3002\u4e24\u8005\u572830\u2103\u63a5\u540824h\uff0c\u5728\u542bX-\u03b1-Gal\u548c300ng\/ml AbA\u7684DDO (SD\/-Leu\/-Trp)\u57f9\u517b\u57fa\u7b5b\u90093-5\u5929\u3002<\/span><\/p>\n

\u6ce8\u610f\u4e8b\u9879<\/strong><\/span><\/p>\n

\u4e3a\u4e86\u60a8\u7684\u5b89\u5168\u548c\u5065\u5eb7\uff0c\u8bf7\u7a7f\u5b9e\u9a8c\u670d\u5e76\u6234\u4e00\u6b21\u6027\u624b\u5957\u64cd\u4f5c\u3002<\/span><\/p>\n

\u9644\u88681 \u91d1\u62c5\u5b50\u7d20\uff08Aureobasidin, AbA\uff09\u5bf9\u4e0d\u540c\u9175\u6bcd\u83cc\u7684\u6700\u4f4e\u6291\u83cc\u6d53\u5ea6<\/strong><\/span><\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u88681 AbA\u5bf9\u4e0d\u540c\u9175\u6bcd\u83cc\u7684\u6700\u4f4e\u6291\u83cc\u6d53\u5ea6\uff08MIC\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u83cc\u682a\u7c7b\u578b<\/span><\/p>\n<\/td>\n

\n

MIC (ng\/ml)<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Saccharomyces cerevisiae\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n

\u917f\u9152\u9175\u6bcd<\/span><\/p>\n<\/td>\n

ATCC9763 (diploid)<\/span><\/td>\n200-400<\/span><\/td>\n<\/tr>\n
\n

SH3328 (haploid)<\/span><\/p>\n<\/td>\n

100<\/span><\/td>\n<\/tr>\n
\n

Sake yeast (diploid)<\/span><\/p>\n<\/td>\n

100-200<\/span><\/td>\n<\/tr>\n
\n

Shochu yeast (diploid)<\/span><\/p>\n<\/td>\n

\n

100<\/span><\/p>\n<\/td>\n<\/tr>\n

Beer yeast (triploid or tetraploid)\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/td>\n\n

100<\/span><\/p>\n<\/td>\n<\/tr>\n

Baker\u2019s yeast (diploid)<\/span><\/td>\n\n

200-400\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Schizosaccharomyces pombe<\/span><\/p>\n

\u7c9f\u9152\u88c2\u6b96\u9175\u6bcd<\/span><\/p>\n<\/td>\n

JY-745 (monoploid)<\/span><\/td>\n100<\/span><\/td>\n<\/tr>\n
Candidaalbicans\u767d\u8272\u5ff5\u73e0\u83cc<\/span><\/td>\nTIMM-0136 (diploid)<\/span><\/td>\n\n

40<\/span><\/p>\n<\/td>\n<\/tr>\n

Candidatropicalis\u70ed\u5e26\u5ff5\u73e0\u83cc<\/span><\/td>\nTIMM-0324 (diploid)<\/span><\/td>\n\n

80<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u00a0\u2014 \u2014Written\/Edited by V. Shallan\u3010\u7248\u6743\u5f52\u96c6\u5947\u751f\u7269\/MKBio\u61cb\u5eb7\u6240\u6709\u3011<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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